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Published 16:33 22 Mar 2017 GMT
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But it's going to be tough and it's a tough fixture anyway. Martin O'Neill has selected a 39-man squad but their options are being ravaged with injury.
Here's how Ireland will actually line out against Wales.
Darren Randolph
The best 'keeper and now he's playing every week for West Ham.
Seamus Coleman
The best player. In the world. Ever.
Richard Keogh
Hard done by of late but injury to Duffy and Clark will surely secure his place in the team.
https://twitter.com/JohnScottie35/status/844235868638531584
John O'Shea
Him and Keogh are the default really.
Stephen Ward
Would deserve his spot even with Brady there. He's been performing well for Ireland and playing every week in the Premier League with Burnley.
James McCarthy
Good player. Has his international mojo back.
David Meyler
Definitely deserves a shot after his performance against Austria but they'll probably opt for Whelan.
https://twitter.com/SportsJOEdotie/status/797557517270351876
Jeff Hendrick
Obviously.
Jon Walters
Obviously.
James McClean
Obviously.
Shane Long
It could be a long night for him but he can stretch the Welsh and excite the Aviva.The SportsJOE Friday Pub Quiz: Week 137
Another big teaser! The SportsJOE Friday Pub Quiz is going nowhere! Give it a crack and good luck!
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